Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 16/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7147781 | 0.83 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL7149312 | 0.82 | P2RY6 (0.54) | PTGS2PTGS1P2RY6 | |
| SCHEMBL6093644 | 0.81 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL7143134 | 0.79 | P2RY6 (0.50) | PTGS2PTGS1P2RY6 | |
| SCHEMBL7149833 | 0.78 | CA12 (0.38) | PTGS2PTGS1 | |
| SCHEMBL7143875 | 0.77 | PTGS2 (0.39) | PTGS2PTGS1P2RY6 | |
| SCHEMBL7149365 | 0.76 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL7151246 | 0.76 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL7142450 | 0.75 | PTGS2 (0.40) | PTGS2PTGS1P2RY6 | |
| SCHEMBL7146217 | 0.75 | PTGS2 (0.44) | PTGS2PTGS1P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |