Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL7146317 | 0.92 | PTGER4 (0.37) | ABHD6PTGER1MAPTTHRBALDH1A1 | |
| Hydrochloric Acid SCHEMBL7146271 | 0.90 | PTGER1 (0.39) | ABHD6MRGPRX4PTGER1MAPK1 | |
| Hydrochloric Acid SCHEMBL7143155 | 0.89 | ABHD6 (0.38) | ABHD6MRGPRX4PTGER1MAPK1NR1H2 | |
| Hydrochloric Acid SCHEMBL7146578 | 0.87 | PTGER1 (0.37) | ABHD6MRGPRX4PTGER1MAPK1 | |
| Hydrochloric Acid SCHEMBL7141769 | 0.86 | PTGER1 (0.41) | ABHD6PTGER1MAPK1 | |
| Hydrochloric Acid SCHEMBL7139220 | 0.85 | PTGER1 (0.47) | MRGPRX4PTGER1MAPK1 | |
| Hydrochloric Acid SCHEMBL7146319 | 0.82 | FAAH (0.36) | PTGER1PTGER4 | |
| SCHEMBL7209116 | 0.81 | GAA (0.38) | ABHD6PTGER1 | |
| SCHEMBL8058096 | 0.81 | CETP (0.38) | ABHD6PTGER1 | |
| Hydrochloric Acid SCHEMBL7144634 | 0.81 | PTGER1 (0.37) | PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056730-A4 | BENZOATE DERIVATIVES OF DIARYL 1,3,4-OXADIAZOLONE | BRISTOL MYERS SQUIBB CO (US) | 2003-01-02 | — | — | EP | claimed |
| EP-1056730-A1 | BENZOATE DERIVATIVES OF DIARYL 1,3,4-OXADIAZOLONE | Bristol-Myers Squibb Company (US) | 2000-12-06 | — | — | EP | claimed |
| WO-1999038854-A1 | BENZOATE DERIVATIVES OF DIARYL 1,3,4-OXADIAZOLONE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-08-05 | — | — | WO | claimed |