SCHEMBL714357

SCHEMBL714357

O=C(OF)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
KDM4E B2RXH2 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
USP2 O75604 1/20 0.36
MAPT P10636 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
HTT P42858 1/20 0.35
GAA P10253 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL713217 1.00 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
SCHEMBL715364 1.00 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
SCHEMBL712408 1.00 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
SCHEMBL713038 1.00 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
SCHEMBL716379 1.00 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
SCHEMBL403954 1.00 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
SCHEMBL720226 1.00 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
SCHEMBL715943 1.00 TSHR (0.39) TSHRKDM4ETDP1USP2MAPT
Water SCHEMBL15939211 0.98 TSHR (0.38) TSHRKDM4ETDP1USP2MAPT
Ammonia Solution, Strong SCHEMBL6997853 0.98 TSHR (0.38) TSHRKDM4ETDP1USP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119286386-A Elastic base material for automobile spraying coating, and preparation method and application thereof 广州波粒新材料科技有限公司 2025-01-10 CN claimed
CN-119080010-A Preparation method and application of organic fluorine modified nano fumed silica 湖北汇富纳米材料股份有限公司 2024-12-06 CN claimed
CN-118483343-A Method for simultaneously detecting multiple new pollutants in coral 广东省环境科学研究院 2024-08-13 CN claimed
CN-118461044-A MOF hydrophobic microenvironment regulation ruthenium nanoparticle catalyst and preparation method and application thereof 中国科学院合肥物质科学研究院 2024-08-09 CN claimed
CN-111848832-B Application of fluorine-containing compound modified cationic polymer as drug carrier and preparation method thereof 苏州大学 2024-02-20 CN claimed
CN-111892667-B Application of fluorine-containing compound modified cationic polymer in preparation of medical cosmetic and health care products 苏州大学 2024-02-20 CN claimed
CN-111848831-B Application of fluorine-containing compound modified cationic polymer in preparation of vaccine medicine 苏州大学 2023-06-13 CN claimed
CN-115475607-A Cationic amphiphilic fluorine-containing hydrogel adsorbent and preparation method and application thereof 安徽农业大学 2022-12-16 CN claimed
EP-4095162-A1 APPLICATION OF AND PREPARATION METHOD FOR CATIONIC POLYMER MODIFIED BY FLUORINE-CONTAINING COMPOUND AS DRUG CARRIER Soochow University (CN) 2022-11-30 EP claimed
US-20220273806-A1 USE OF FLUORINE-CONTAINING COMPOUND-MODIFIED CATIONIC POLYMER AS DRUG CARRIER AND PREPARATION METHOD SOOCHOW UNIVERSITY (CN) 2022-09-01 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
EP-1431984-A1 Polymer resistor composition having a substantially neutral temperature coefficient of resistance and methods and compositions relating thereto E. I. du Pont de Nemours and Company (US) 2004-06-23 EP claimed
US-20040113127-A1 Resistor compositions having a substantially neutral temperature coefficient of resistance and methods and compositions relating thereto E.I. DU PONT DE NEMOURS AND COMPANY 2004-06-17 US claimed
US-20030099424-A1 Optical gain media and methods for making and using same MOHAJER YOUSEF (US) 2003-05-29 US claimed
WO-2003018592-A1 OPTICAL GAIN MEDIA PHOTON-X, INC. (US) 2003-03-06 WO claimed
EP-1288727-A2 Polydimethylsiloxane and fluorosurfactant fusing release agent Xerox Corporation (US) 2003-03-05 EP claimed
US-6515069-B1 A release agent having a polydimethylsiloxane and a fluorosurfactant other than a silicone glycol polymer, a perfluoroalkylsubstituted polyethylene glycol, or a perfluoroalkylsubstituted silane. XEROX CORPORATION 2003-02-04 US claimed
US-6383274-B1 Ink jet ink compositions and printing processes XEROX CORPORATION 2002-05-07 US claimed
EP-1005651-A1 METHODS OF IDENTIFYING BIOLOGICAL AGENT COMPOSITIONS SUPRATEK PHARMA, INC. (CA) 2000-06-07 EP claimed
WO-1999008112-A1 METHODS OF IDENTIFYING BIOLOGICAL AGENT COMPOSITIONS SUPRATEK PHARMA INC. (CA) 1999-02-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273806-A1 USE OF FLUORINE-CONTAINING COMPOUND-MODIFIED CATIONIC POLYMER AS DRUG CARRIER AND PREPARATION METHOD F12, SLCO4C1, SLC7A1 TSHR 111/4885KDM4E 989/4885TDP1 4195/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 TSHR 4082/4885KDM4E 1567/4885TDP1 1182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.