Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 17/20 | 0.55 |
| ▸ | CA2 | P00918 | 17/20 | 0.55 |
| ▸ | CA12 | O43570 | 15/20 | 0.55 |
| ▸ | CA7 | P43166 | 10/20 | 0.55 |
| ▸ | CA13 | Q8N1Q1 | 10/20 | 0.55 |
| ▸ | CA6 | P23280 | 9/20 | 0.55 |
| ▸ | CA9 | Q16790 | 7/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30512098 | 1.00 | CA1 (0.55) | CA1CA2CA12CA7CA13 | |
| SCHEMBL30512097 | 1.00 | CA1 (0.55) | CA1CA2CA12CA7CA13 | |
| SCHEMBL7912398 | 0.84 | HSD11B1 (0.46) | CA1CA2CA12CA7CA13 | |
| SCHEMBL7914192 | 0.84 | CA2 (0.51) | CA1CA2CA12CA7CA13 | |
| SCHEMBL8622834 | 0.83 | CA2 (0.47) | CA1CA2CA12CA7CA13 | |
| SCHEMBL1185507 | 0.82 | CA1 (0.58) | CA1CA2CA12CA7CA13 | |
| SCHEMBL28574241 | 0.80 | CA1 (0.60) | CA1CA2CA12CA7CA13 | |
| SCHEMBL7914241 | 0.79 | CA1 (0.58) | CA1CA2CA12CA7CA13 | |
| SCHEMBL7410393 | 0.79 | CA1 (0.58) | CA1CA2CA12CA7CA13 | |
| SCHEMBL2300229 | 0.79 | CA1 (0.70) | CA1CA2CA12CA9STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876482-A | Polysubstituted heterocyclic derivative, preparation method and medical application thereof | 中国药科大学 | 2021-06-01 | — | — | CN | disclosed |
| EP-0964849-B1 | SULFONYL UREA DERIVATIVES AND THEIR USE IN THE CONTROL OF INTERLEUKIN-1 ACTIVITY | PFIZER (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-1270565-A1 | 4-Substituted furan-2-sulfonamide and its use in the preparation of sulfonyl urea derivatives | PFIZER INC. (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-1270554-A1 | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity | PFIZER INC. (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |
| US-6166064-A | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity | PFIZER INC (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0964849-A1 | SULFONYL UREA DERIVATIVES AND THEIR USE IN THE CONTROL OF INTERLEUKIN-1 ACTIVITY | PFIZER INC. (US) | 1999-12-22 | — | — | EP | disclosed |
| WO-1998032733-A1 | SULFONYL UREA DERIVATIVES AND THEIR USE IN THE CONTROL OF INTERLEUKIN-1 ACTIVITY | PFIZER INC. (US) | 1998-07-30 | — | — | WO | disclosed |