Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7179272 | 0.83 | MEN1 (0.68) | MEN1KMT2ADRD2SIGMAR1CHRM4 | |
| SCHEMBL1002852 | 0.82 | MEN1 (0.81) | MEN1KMT2ADRD2SIGMAR1CHRM4 | |
| SCHEMBL2332535 | 0.81 | MEN1 (0.74) | MEN1KMT2ADRD2SIGMAR1CHRM4 | |
| SCHEMBL3153917 | 0.81 | MEN1 (0.74) | MEN1KMT2ADRD2SIGMAR1HDAC3 | |
| SCHEMBL8775737 | 0.81 | MEN1 (0.74) | MEN1KMT2ADRD2SIGMAR1DRD4 | |
| SCHEMBL6070072 | 0.81 | GAA (0.70) | MEN1KMT2ADRD2CHRM4HDAC3 | |
| Hydrochloric Acid SCHEMBL7985714 | 0.80 | MEN1 (0.72) | MEN1KMT2ADRD2SIGMAR1DRD4 | |
| SCHEMBL4178029 | 0.79 | SLC18A3 (0.58) | MEN1KMT2ADRD2SIGMAR1GAA | |
| SCHEMBL28742579 | 0.78 | HDAC1 (0.72) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL6223362 | 0.78 | MEN1 (0.70) | MEN1KMT2ADRD2SIGMAR1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355888-A1 | QUINAZOLINONE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002048117-A1 | QUINAZOLINONE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-20 | — | — | WO | disclosed |