Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | DRD2 | P14416 | 6/20 | 0.58 |
| ▸ | DRD4 | P21917 | 4/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | CCR5 | P51681 | 1/20 | 0.55 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.53 |
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1002852 | 0.88 | MEN1 (0.81) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL3153917 | 0.84 | MEN1 (0.74) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL7329656 | 0.84 | MEN1 (0.74) | MEN1KMT2ADRD2DRD4CHRM4 | |
| SCHEMBL19222078 | 0.84 | MEN1 (0.74) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL8775737 | 0.84 | MEN1 (0.74) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL7179272 | 0.83 | MEN1 (0.68) | MEN1KMT2ADRD2DRD4CHRM4 | |
| Hydrochloric Acid SCHEMBL7985714 | 0.83 | MEN1 (0.72) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL6223362 | 0.81 | MEN1 (0.70) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL3157794 | 0.81 | TRPV6 (0.77) | MEN1KMT2ACCR5TRPV6SIGMAR1 | |
| SCHEMBL7144058 | 0.81 | MEN1 (0.65) | MEN1KMT2ADRD2DRD4CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011100380-A1 | ARYLMETHOXY ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | CELGENE CORPORATION (US) | 2011-08-18 | — | — | WO | disclosed |