SCHEMBL7144067

SCHEMBL7144067

O=C(O)C1(C2CCC3OC32)CCC2OC2C1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.34
GMNN O75496 2/20 0.33
LMNA P02545 2/20 0.33
PMP22 Q01453 2/20 0.33
TP53 P04637 2/20 0.33
NFKB1 P19838 2/20 0.33
THPO P40225 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TFPI2 P48307 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 2/20 0.31
CYP2C19 P33261 1/20 0.31
STAT6 P42226 1/20 0.31
HIF1A Q16665 1/20 0.31
NPC1 O15118 1/20 0.31
MTOR P42345 1/20 0.31
RAB9A P51151 1/20 0.31
BLM P54132 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11590884 0.91 CYP19A1 (0.30) CYP19A1
SCHEMBL36696 0.75 TFPI2 (0.34) CYP19A1GMNNLMNAPMP22TP53
SCHEMBL7144478 0.75
SCHEMBL28298764 0.73 LMNA (0.32) GMNNLMNAPMP22TP53NFKB1
SCHEMBL4612128 0.72 PPP5C (0.33) GMNNLMNAPMP22TP53NFKB1
SCHEMBL28907233 0.71 PPP5C (0.33) GMNNLMNAPMP22TP53NFKB1
SCHEMBL28323858 0.71
SCHEMBL28457625 0.69 EPHX1 (0.38)
SCHEMBL9501569 0.69
SCHEMBL9656017 0.67 LMNA (0.39) GMNNLMNAPMP22TP53NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6632523-B1 Polyimidesiloxane made from a dianhydride, an aromatic diamine and a siloxanediamine, an epoxy resin, and a cyanate; tape SUMITOMO BAKELITE COMPANY LIMITED (JP) 2003-10-14 US disclosed
WO-2002026888-A2 LOW TEMPERATURE BONDING ADHESIVE COMPOSITION SUMITOMO BAKELITE COMPANY LIMITED (JP) 2002-04-04 WO disclosed
US-5935372-A A BLEND COMPRISING SOLVENT, A CURABLE IMIDIZED POLYIMIDESILOXANE COPOLYMER AND AN EPOXY RESIN CURING AGENT; STORAGE STABILITY, NO EXTRA HEATING STEP WHEN PACKAGE IS MOUNTED ON A CIRCUIT BOARD OCCIDENTAL CHEMICAL CORPORATION (US) 1999-08-10 US disclosed
US-4038338-A NEW POLYEPOXIDE-POLYSILOXANE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1977-07-26 US disclosed