Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | THPO | P40225 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27993146 | 0.78 | LMNA (0.39) | LMNAMAPK1TP53NFKB1THPO | |
| SCHEMBL1547983 | 0.75 | MAPK1 (0.45) | LMNAMAPK1TP53NFKB1THPO | |
| SCHEMBL28194331 | 0.75 | MAPK1 (0.36) | LMNAMAPK1TP53NFKB1THPO | |
| SCHEMBL175503 | 0.74 | MAPK1 (0.35) | LMNAMAPK1TP53NFKB1THPO | |
| SCHEMBL16005 | 0.74 | MAPK1 (0.35) | LMNAMAPK1TP53NFKB1THPO | |
| SCHEMBL28539549 | 0.72 | MAPK1 (0.34) | LMNAMAPK1TP53NFKB1THPO | |
| SCHEMBL27957856 | 0.72 | MAPK1 (0.38) | LMNAMAPK1TP53NFKB1THPO | |
| SCHEMBL1860545 | 0.71 | MAPK1 (0.37) | LMNAMAPK1TP53NFKB1THPO | |
| SCHEMBL6849350 | 0.71 | MAPK1 (0.33) | LMNAMAPK1TP53NFKB1THPO | |
| SCHEMBL741407 | 0.71 | MAPK1 (0.37) | LMNAMAPK1TP53NFKB1THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3317318-B1 | A THERMOSETTING EPOXY RESIN COMPOSITION FOR THE PREPARATION OF OUTDOOR ARTICLES, AND THE ARTICLES OBTAINED THEREFROM | HUNTSMAN ADV MAT LICENSING SWITZERLAND GMBH (CH) | 2019-04-24 | — | — | EP | claimed |
| CN-104840449-B | A kind of medicine patch and preparation method thereof | 崔建平 | 2018-05-18 | — | — | CN | disclosed |
| EP-0479166-A1 | Transesterification process for preparation of cycloaliphatic epoxides | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1992-04-08 | — | — | EP | disclosed |