SCHEMBL7144129

SCHEMBL7144129

COC(=O)C(CCSC)NC(=O)c1ccc(SCc2ccccn2)cc1-c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.55
FNTB P49356 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
KMT2A Q03164 1/20 0.54
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7144133 1.00 FNTA (0.55) FNTAFNTBTDP1KMT2ARAB9A
SCHEMBL6624205 0.86 FNTA (0.56) FNTAFNTBTDP1KMT2A
SCHEMBL7140058 0.80 FNTA (0.56) FNTAFNTBTDP1KMT2A
SCHEMBL6772100 0.80 FNTA (0.56) FNTAFNTBTDP1KMT2A
SCHEMBL6774794 0.80 FNTA (0.61) FNTAFNTBTDP1KMT2A
SCHEMBL7143732 0.80 L3MBTL1 (0.46) KMT2ARAB9A
SCHEMBL7138598 0.80 FNTA (0.56) FNTAFNTBTDP1KMT2ARAB9A
SCHEMBL6777591 0.80 FNTA (0.56) FNTAFNTBTDP1KMT2ARAB9A
SCHEMBL6777742 0.79 FNTA (0.55) FNTAFNTBTDP1
SCHEMBL6777738 0.79 FNTA (0.55) FNTAFNTBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873123-B1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIV PITTSBURGH (US) 2003-04-09 EP disclosed