Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144288 | 1.00 | SCN3A (0.56) | SCN3AMAOAMAOBBCHEADRA2B | |
| Hydrochloric Acid SCHEMBL195248 | 0.98 | SCN3A (0.55) | SCN3AMAOAMAOBBCHEADRA2B | |
| SCHEMBL5193757 | 0.91 | ALDH1A1 (0.58) | TAS1R3TAS1R1TAS1R2ALDH1A1HTT | |
| SCHEMBL2467861 | 0.86 | MAOA (0.56) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL30341899 | 0.86 | MAOA (0.56) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL92713 | 0.86 | MAOA (0.56) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL3932599 | 0.86 | MAOA (0.56) | MAOAMAOBBCHEADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL5969990 | 0.84 | MAOA (0.55) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL21447835 | 0.84 | MAOA (0.55) | SCN3AMAOAMAOBBCHEADRA2B | |
| SCHEMBL11145013 | 0.84 | MAOA (0.55) | MAOAMAOBBCHEADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1211351-C | Alpha-amino acid amides, prepn. thereof and the therapeutic use thereof | CHIESI FARMA SPA (IT) | 2005-07-20 | — | — | CN | disclosed |
| EP-0951465-B1 | ALPHA-AMINO ACID AMIDES, PREPARATION THEREOF AND THE THERAPEUTICAL USE THEREOF | CHIESI FARMA SPA (IT) | 2003-04-16 | — | — | EP | disclosed |
| US-6114391-A | A DERIVATIVES OF SERINAMIDE, GLYCINAMIDE, ALANINAMIDE AND PHENYLALANINAMIDE FOR TREATING NEUROLOGICAL DISEASES | CHIESI FARMACEUTICI S.P.A. (IT) | 2000-09-05 | — | — | US | disclosed |
| CN-1225625-A | Alpha-amino acid amides, prepn. thereof and the therapeutic use thereof | CHIESI FARMA SPA (IT) | 1999-08-11 | — | — | CN | disclosed |