SCHEMBL7144364

SCHEMBL7144364

CCCC(=O)Nc1ccc(F)c([Ti])c1F

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.47
POLB P06746 2/20 0.47
GAA P10253 1/20 0.47
KDM4E B2RXH2 2/20 0.44
PKM P14618 1/20 0.44
TP53 P04637 1/20 0.44
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
EPHX2 P34913 1/20 0.43
HTT P42858 1/20 0.42
ALPL P05186 1/20 0.42
ALPI P09923 1/20 0.42
ALPG P10696 1/20 0.42
LMNA P02545 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
F2R P25116 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7580934 0.91 CETP (0.48) POLBGAAKDM4EALDH1A1EPHX2
SCHEMBL27527865 0.82 EPHX2 (0.39) POLBKDM4EALDH1A1MEN1KMT2A
SCHEMBL20399224 0.80 KDM4E (0.50) MAPK1POLBGAAKDM4EPKM
SCHEMBL27483566 0.80 RAB9A (0.65) MAPK1POLBGAAKDM4EALDH1A1
SCHEMBL27468288 0.78 SMN1; SMN2 (0.38) POLBKDM4ETP53ALDH1A1MEN1
SCHEMBL7137151 0.78 HDAC1 (0.46) POLBGAAKDM4EPKMALDH1A1
SCHEMBL27466875 0.77 MEN1 (0.50) POLBGAAALDH1A1MEN1KMT2A
SCHEMBL7580924 0.76 KDM4E (0.47) GAAKDM4EPKMALDH1A1KMT2A
SCHEMBL27515371 0.76 EPHX2 (0.41) POLBGAAKDM4EALDH1A1MEN1
SCHEMBL27515372 0.76 ALDH1A1 (0.50) POLBTP53ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1215379-C Original edition for lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2005-08-17 CN disclosed
US-20030190554-A1 Photopolymerization; development using alkalinity developer FUJIFILM CORPORATION (JP) 2003-10-09 US disclosed
CN-1425068-A Fungal transcriptional activator useful in methods of producing polypeptides NOVOZYMES AS (DK) 2003-06-18 CN disclosed
CN-1374559-A Original edition for lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2002-10-16 CN disclosed