Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7137112 | 0.84 | PIK3CD (0.41) | PIK3CDRNPEPSLC7A5MMECPA1 | |
| SCHEMBL5718288 | 0.82 | GABRA1 (0.40) | PIK3CDGABRA1GABRG2GABRB3ALDH1A1 | |
| SCHEMBL5718295 | 0.81 | GABRA1 (0.39) | PIK3CDGABRA1GABRG2GABRB3ALDH1A1 | |
| SCHEMBL7140859 | 0.81 | GABRA1 (0.49) | PIK3CDGABRA1GABRG2GABRB3ALDH1A1 | |
| SCHEMBL7136332 | 0.81 | GABRA1 (0.49) | PIK3CDGABRA1GABRG2GABRB3ALDH1A1 | |
| SCHEMBL7041880 | 0.79 | SLC1A3 (0.41) | RNPEPSLC7A5CPA1MAPTALDH1A1 | |
| SCHEMBL7041883 | 0.79 | SLC1A3 (0.41) | RNPEPSLC7A5CPA1MAPTALDH1A1 | |
| SCHEMBL7140882 | 0.78 | CHRM1 (0.43) | PIK3CDGABRA1GABRG2GABRB3ALDH1A1 | |
| SCHEMBL7144010 | 0.78 | CHRM1 (0.43) | PIK3CDGABRA1GABRG2GABRB3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7431962 | 0.76 | CHRM1 (0.42) | GABRA1GABRG2GABRB3SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098871-B1 | alpha-AMINO ACID PHENYL ESTER DERIVATIVES | AKZO NOBEL NV (NL) | 2003-07-09 | — | — | EP | disclosed |
| US-6451854-B1 | α-amino acid phenyl ester derivatives | AKZO NOBEL N.V. (NL) | 2002-09-17 | — | — | US | disclosed |