Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6284312 | 0.98 | CYP19A1 (0.51) | CYP19A1CYP11B1CYP11B2KMT2AALOX15 | |
| SCHEMBL7149156 | 0.86 | CYP17A1 (0.49) | CYP19A1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7140967 | 0.86 | SMN1; SMN2 (0.51) | NAMPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL7149214 | 0.85 | POLB (0.51) | CYP11B1CYP11B2KMT2AMEN1ALDH1A1 | |
| SCHEMBL7142799 | 0.85 | NAMPT (0.49) | KMT2ANAMPTALDH1A1LMNAMAPT | |
| Bromide SCHEMBL6279795 | 0.85 | CYP17A1 (0.48) | CYP19A1KMT2AALDH1A1LMNAMAPT | |
| Bromide SCHEMBL6282444 | 0.84 | SMN1; SMN2 (0.50) | NAMPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL7141524 | 0.84 | NPSR1 (0.52) | KMT2AALOX15CYP3A4MEN1ALDH1A1 | |
| Bromide SCHEMBL6283209 | 0.84 | POLB (0.50) | CYP11B1CYP11B2KMT2AMEN1ALDH1A1 | |
| Bromide SCHEMBL6276160 | 0.84 | NAMPT (0.48) | KMT2ANAMPTALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620825-B1 | 1,3-Azole compound substituted by pyridyl; administering as antiasthmatic, antiinflammatory or antiallergen agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-16 | — | — | US | disclosed |
| US-6436966-B1 | Adenosine A3 receptor antagonists | TAKEDA CHEMICAL IND., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |