Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6276160 | 0.98 | NAMPT (0.48) | NAMPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL7142887 | 0.87 | TDP1 (0.47) | KMT2AALDH1A1NPC1RAB9AKCNA5 | |
| SCHEMBL7149156 | 0.86 | CYP17A1 (0.49) | KMT2AALDH1A1RAB9AGAAMAPT | |
| SCHEMBL7140967 | 0.86 | SMN1; SMN2 (0.51) | NAMPTALDH1A1KCNA5GAALMNA | |
| Bromide SCHEMBL6279797 | 0.85 | TDP1 (0.46) | KMT2AALDH1A1NPC1RAB9AKCNA5 | |
| SCHEMBL7149214 | 0.85 | POLB (0.51) | KMT2AALDH1A1RAB9APTGS2GAA | |
| Bromide SCHEMBL6279795 | 0.85 | CYP17A1 (0.48) | KMT2AALDH1A1NPC1RAB9AGAA | |
| SCHEMBL7144713 | 0.85 | CYP19A1 (0.53) | NAMPTKMT2AALDH1A1NPC1RAB9A | |
| Bromide SCHEMBL6282444 | 0.84 | SMN1; SMN2 (0.50) | NAMPTALDH1A1KCNA5GAALMNA | |
| SCHEMBL7148265 | 0.84 | NPC1 (0.51) | KMT2AALDH1A1NPC1RAB9AKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620825-B1 | 1,3-Azole compound substituted by pyridyl; administering as antiasthmatic, antiinflammatory or antiallergen agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-16 | — | — | US | disclosed |
| US-6436966-B1 | Adenosine A3 receptor antagonists | TAKEDA CHEMICAL IND., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |