Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662136 | 0.95 | MEN1 (0.43) | KMT2AMEN1TSHRSLC1A1KDM5A | |
| SCHEMBL20814001 | 0.84 | KMT2A (0.46) | KMT2AMEN1TSHRSLC1A1KDM5A | |
| SCHEMBL8816379 | 0.83 | MEN1 (0.42) | KMT2AMEN1TSHRSLC1A1KDM5A | |
| SCHEMBL12563519 | 0.82 | MEN1 (0.41) | KMT2AMEN1TSHRSLC1A1KDM5A | |
| SCHEMBL12563524 | 0.82 | MEN1 (0.41) | KMT2AMEN1TSHRSLC1A1KDM5A | |
| SCHEMBL8660845 | 0.81 | KMT2A (0.43) | KMT2AMEN1TSHRSLC1A1KDM5A | |
| SCHEMBL20814075 | 0.77 | MEN1 (0.40) | KMT2AMEN1TSHRSLC1A1KDM5A | |
| SCHEMBL7136332 | 0.77 | GABRA1 (0.49) | HPGDALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL7140859 | 0.77 | GABRA1 (0.49) | HPGDALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL17232315 | 0.74 | KMT2A (0.56) | KMT2AMEN1TSHRSLC1A1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098871-B1 | alpha-AMINO ACID PHENYL ESTER DERIVATIVES | AKZO NOBEL NV (NL) | 2003-07-09 | — | — | EP | disclosed |
| US-6451854-B1 | α-amino acid phenyl ester derivatives | AKZO NOBEL N.V. (NL) | 2002-09-17 | — | — | US | disclosed |