Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662136 | 0.87 | MEN1 (0.43) | KMT2AMEN1TSHRKDM5ACA2 | |
| SCHEMBL7145075 | 0.81 | KMT2A (0.47) | KMT2AMEN1TSHRKDM5AGABRA1 | |
| Acrylic Acid SCHEMBL28082541 | 0.79 | CA1 (0.35) | KMT2AMEN1TSHRCA2CA1 | |
| SCHEMBL8816379 | 0.79 | MEN1 (0.42) | KMT2AMEN1TSHRKDM5ACA2 | |
| SCHEMBL12563524 | 0.78 | MEN1 (0.41) | KMT2AMEN1TSHRKDM5ACA12 | |
| SCHEMBL15518639 | 0.77 | CA2 (0.41) | TSHRCA2CA1GABRA1GABRG2 | |
| SCHEMBL8375570 | 0.77 | GABRA1 (0.39) | CA2CA1GABRA1GABRG2GABRB3 | |
| SCHEMBL12563519 | 0.74 | MEN1 (0.41) | KMT2AMEN1TSHRKDM5ACA12 | |
| SCHEMBL5479656 | 0.74 | CA1 (0.41) | KMT2AMEN1CA2CA1GABRA1 | |
| SCHEMBL10251092 | 0.71 | CA1 (0.38) | KMT2AMEN1CA2CA1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756508-A | Muscarine antagonists | MERCK & CO., INC. (US) | 1998-05-26 | — | — | US | disclosed |
| WO-1997016192-A1 | MUSCARINE ANTAGONISTS | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | disclosed |