Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14249653 | 0.82 | — | — | |
| SCHEMBL4671436 | 0.77 | — | — | |
| SCHEMBL4748100 | 0.75 | CYP3A4 (0.31) | MAPK1 | |
| SCHEMBL2670466 | 0.73 | GAA (0.35) | — | |
| SCHEMBL14699482 | 0.73 | — | — | |
| SCHEMBL21602004 | 0.67 | SLC6A2 (0.38) | — | |
| SCHEMBL15897448 | 0.66 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL10396311 | 0.65 | ALDH1A1 (0.32) | — | |
| SCHEMBL2318788 | 0.65 | TSHR (0.32) | MAPK1 | |
| SCHEMBL585092 | 0.64 | CYP17A1 (0.36) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |