SCHEMBL71453

SCHEMBL71453

O=C(O)CCc1ccccc1-c1ccccc1CCC(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 7/20 0.68
PTGER3 P43115 7/20 0.68
PTGER1 P34995 6/20 0.68
PTGER2 P43116 6/20 0.68
KEAP1 Q14145 1/20 0.58
FFAR1 O14842 5/20 0.54
FFAR4 Q5NUL3 3/20 0.49
HDAC3 O15379 1/20 0.48
MAPK1 P28482 1/20 0.48
ADRA1A P35348 1/20 0.48
HDAC4 P56524 1/20 0.48
SLC6A3 Q01959 1/20 0.48
HDAC1 Q13547 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31212507 0.90 PTGER4 (0.77) PTGER4PTGER3PTGER1PTGER2KEAP1
SCHEMBL1261128 0.90 PTGER4 (0.77) PTGER4PTGER3PTGER1PTGER2KEAP1
SCHEMBL7341280 0.89 PTGER4 (0.57) PTGER4PTGER3PTGER1PTGER2KEAP1
SCHEMBL59198 0.88 KEAP1 (0.65) PTGER4PTGER3PTGER1PTGER2KEAP1
SCHEMBL6053663 0.88 PTGER4 (0.81) PTGER4PTGER3PTGER1PTGER2KEAP1
SCHEMBL8780386 0.86 CYSLTR2 (0.58) PTGER4PTGER3PTGER1PTGER2
SCHEMBL3810456 0.84 PTGER4 (0.56) PTGER4PTGER3PTGER1PTGER2FFAR1
SCHEMBL9484842 0.84 CYSLTR2 (0.60) PTGER4PTGER3PTGER1PTGER2
SCHEMBL8479912 0.84 PTGER4 (0.70) PTGER4PTGER3PTGER1PTGER2KEAP1
SCHEMBL5156821 0.83 PTGER4 (0.64) PTGER4PTGER3PTGER1PTGER2FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 PTGER4 664/4885PTGER3 1131/4885PTGER1 1393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.