SCHEMBL59198

SCHEMBL59198

O=C(O)CCc1ccccc1CCC(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.65
FFAR1 O14842 6/20 0.60
PTGER1 P34995 4/20 0.58
PTGER4 P35408 4/20 0.58
PTGER3 P43115 4/20 0.58
PTGER2 P43116 4/20 0.58
HDAC3 O15379 1/20 0.54
MAPK1 P28482 1/20 0.54
ADRA1A P35348 1/20 0.54
HDAC4 P56524 1/20 0.54
SLC6A3 Q01959 1/20 0.54
HDAC1 Q13547 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC10 Q969S8 1/20 0.54
HDAC11 Q96DB2 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
HDAC9 Q9UKV0 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8019696 0.91 AKR1B1 (0.59) KEAP1FFAR1PTGER1PTGER4PTGER3
SCHEMBL878984 0.91 KEAP1 (0.56) KEAP1FFAR1PTGER1PTGER4PTGER3
SCHEMBL3728799 0.91 CYP4F2 (0.58) KEAP1FFAR1PTGER1PTGER4PTGER3
SCHEMBL8573204 0.91 KEAP1 (0.56) KEAP1FFAR1PTGER1PTGER4PTGER3
SCHEMBL8851286 0.89 KEAP1 (0.54) KEAP1FFAR1PTGER1PTGER4PTGER3
SCHEMBL19140662 0.89 FOLH1 (0.60) KEAP1FFAR1PTGER1PTGER4PTGER3
SCHEMBL22826567 0.89 MAPT (0.62) KEAP1FFAR1PTGER1PTGER4PTGER3
SCHEMBL4172963 0.89 KEAP1 (0.54) KEAP1FFAR1PTGER1PTGER4PTGER3
SCHEMBL8109289 0.89 KEAP1 (0.54) KEAP1FFAR1PTGER1PTGER4PTGER3
SCHEMBL9425235 0.89 KEAP1 (0.54) KEAP1FFAR1PTGER1PTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024044062-A1 THERMOPLASTIC PARTICULATES AND METHOD TO MAKE THEM Jabil Inc. (US) 2024-02-29 WO claimed
US-20170365729-A1 NANOWIRE COMPOSITE STRUCTURE AND METHODS OF FORMING THE SAME, SENSING DEVICE AND METHODS OF FORMING THE SAME AND PROTECTIVE STRUCTURES OF A NANOWIRE NATIONAL TSING HUA UNIVERSITY (TW) 2017-12-21 US claimed
WO-2014022666-A1 CROSSLINKED NATIVE AND WAXY STARCH RESIN COMPOSITIONS AND PROCESSES FOR THEIR MANUFACTURE CORNELL UNIVERSITY (US) 2014-02-06 WO claimed
CN-102112327-B Tyre and crosslinkable elastomeric composition comprising an oxetane derivative and a carboxylic acid PIRELLI 2013-11-20 CN claimed
US-8129092-B2 Resist pattern thickening material and process for forming resist pattern, and semiconductor device and method for manufacturing the same FUJITSU LIMITED (JP) 2012-03-06 US claimed
CN-102112327-A Tyre and crosslinkable elastomeric composition comprising an oxetane derivative and a carboxylic acid PIRELLI 2011-06-29 CN claimed
EP-1893643-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING HIV INFECTION YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2008-03-05 EP claimed
WO-2006137075-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING HIV INFECTION YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-12-28 WO claimed
EP-0912166-B1 METHODS AND COMPOSITIONS FOR ENHANCING THE BIOADHESIVE PROPERTIES OF POLYMERS USING ORGANIC EXCIPIENTS UNIV BROWN RES FOUND (US) 2003-01-15 EP claimed
US-20010000142-A1 Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients SANTOS CAMILA A (US) 2001-04-05 US claimed
US-5955096-A POLYANHYDRIDES ANND BIOADHESIVE POLYMERS BROWN UNIVERSITY RESEARCH FOUNDATION (US) 1999-09-21 US claimed
EP-0912166-A1 METHODS AND COMPOSITIONS FOR ENHANCING THE BIOADHESIVE PROPERTIES OF POLYMERS USING ORGANIC EXCIPIENTS BROWN UNIVERSITY RESEARCH FOUNDATION (US) 1999-05-06 EP claimed
WO-1997049385-A1 METHODS AND COMPOSITIONS FOR ENHANCING THE BIOADHESIVE PROPERTIES OF POLYMERS USING ORGANIC EXCIPIENTS BROWN UNIVERSITY RESEARCH FOUNDATION (US) 1997-12-31 WO claimed
US-4888176-A BIOCOMPATIBLE THIN FILMS OF SOLVENT-CAST COPOLYMERS; TENSILE STRENGTH MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1989-12-19 US claimed
US-4757128-A Produced from aliphatic or aromatic or heterocyclic dicarboxylic acid MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1988-07-12 US claimed
EP-0266603-A1 Preparation of anhydride copolymers MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1988-05-11 EP claimed
EP-0260415-A2 Synthesis and application of high molecular weight polyanhydrides MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1988-03-23 EP claimed
US-12528973-B2 Composition and method for silicon oxide and carbon doped silicon oxide CMP CMC MATERIALS LLC (US) 2026-01-20 US disclosed
US-4045510-A POLYAMIDES, POLYESTERS, AND POLYURETHANES COATED WITH AN ANTISTATIC RENDERING POLYETHER BASF WYANDOTTE CORPORATION (US) 1977-08-30 US disclosed
US-3950310-A FIBERS, MOLDING MATERIALS EXXON RESEARCH & ENGINEERING CO. (US) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528973-B2 Composition and method for silicon oxide and carbon doped silicon oxide CMP PIEZO1, OCIAD2, CLK2 KEAP1 4364/4885FFAR1 3659/4885PTGER1 2893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.