Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 13/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7143875 | 0.84 | PTGS2 (0.39) | PTGS2PTGS1P2RY6ADRB3ADRA2B | |
| SCHEMBL7142807 | 0.83 | P2RY6 (0.38) | PTGS2PTGS1P2RY6 | |
| SCHEMBL7149312 | 0.82 | P2RY6 (0.54) | PTGS2PTGS1P2RY6 | |
| SCHEMBL7149796 | 0.81 | PTGS2 (0.37) | PTGS2PTGS1P2RY6 | |
| SCHEMBL6091947 | 0.81 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL6093621 | 0.81 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7145416 | 0.81 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL7142828 | 0.80 | PTGS2 (0.47) | PTGS2PTGS1P2RY6 | |
| Fluoride SCHEMBL20636890 | 0.80 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL7148749 | 0.77 | PTGS2 (0.41) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |