Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11005852 | 0.86 | CA1 (0.50) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11003933 | 0.81 | ALDH1A1 (0.47) | CA1CA2KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11003886 | 0.80 | ALDH1A1 (0.46) | CA1CA2KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7140757 | 0.78 | KDM1A (0.36) | CA1CA2ALDH1A1 | |
| SCHEMBL14198135 | 0.76 | CA1 (0.53) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL27490005 | 0.76 | CA1 (0.58) | CA1CA2KMT2AMEN1KDM4E | |
| SCHEMBL399565 | 0.75 | KDM1A (0.50) | CA1CA2ALDH1A1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL4869944 | 0.73 | KDM1A (0.49) | CA1CA2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL8688541 | 0.73 | DRD2 (0.56) | CA1CA2ALDH1A1CYP2C9CYP2D6 | |
| SCHEMBL11896157 | 0.73 | CA1 (0.54) | CA1CA2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951465-B1 | ALPHA-AMINO ACID AMIDES, PREPARATION THEREOF AND THE THERAPEUTICAL USE THEREOF | CHIESI FARMA SPA (IT) | 2003-04-16 | — | — | EP | disclosed |
| US-6114391-A | A DERIVATIVES OF SERINAMIDE, GLYCINAMIDE, ALANINAMIDE AND PHENYLALANINAMIDE FOR TREATING NEUROLOGICAL DISEASES | CHIESI FARMACEUTICI S.P.A. (IT) | 2000-09-05 | — | — | US | disclosed |