Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 13/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092923 | 0.82 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL6094173 | 0.82 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL7143134 | 0.78 | P2RY6 (0.50) | PTGS2PTGS1P2RY6 | |
| SCHEMBL5648251 | 0.75 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL7146266 | 0.75 | PTGS2 (0.67) | PTGS2PTGS1P2RY6 | |
| SCHEMBL6790596 | 0.74 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL7145006 | 0.72 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL6790598 | 0.72 | PTGS2 (0.38) | PTGS2PTGS1NR1H4CA12CA1 | |
| SCHEMBL5644179 | 0.72 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL7149501 | 0.72 | PTGS2 (0.40) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |