Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25142645 | 0.90 | GHSR (0.47) | GHSRACETRPM8 | |
| SCHEMBL7155681 | 0.87 | MTNR1B (0.49) | ACETRPM8DRD2MTNR1BMTNR1A | |
| SCHEMBL7152377 | 0.83 | ACE (0.60) | ACEMTNR1BMTNR1A | |
| SCHEMBL605316 | 0.82 | ACE (0.56) | GHSRACEMTNR1B | |
| SCHEMBL30310636 | 0.82 | ACE (0.56) | GHSRACEMTNR1B | |
| SCHEMBL29560869 | 0.82 | ACE (0.56) | GHSRACEMTNR1B | |
| SCHEMBL14744581 | 0.82 | ACE (0.56) | GHSRACEMTNR1B | |
| SCHEMBL18066415 | 0.82 | ACE (0.56) | GHSRACEMTNR1B | |
| SCHEMBL5965344 | 0.82 | ACE (0.46) | ACEMTNR1BMTNR1A | |
| SCHEMBL7702856 | 0.82 | ACE (0.46) | ACEMTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1515550-A | Thrombosis resisting preparation | — | 2004-07-28 | — | — | CN | disclosed |
| EP-1361212-A1 | Peptide derivatives as antithrombotic agents | AstraZeneca AB (SE) | 2003-11-12 | — | — | EP | disclosed |
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | disclosed |
| US-6214841-B1 | ANTICOAGULANTS | ELI LILLY AND COMPANY | 2001-04-10 | — | — | US | disclosed |
| US-5914319-A | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1999-06-22 | — | — | US | disclosed |
| EP-0884326-A2 | Antithrombitic compound | ELI LILLY AND COMPANY (US) | 1998-12-16 | — | — | EP | disclosed |
| WO-1998051684-A1 | ANTITHROMBOTIC COMPOUND | ELI LILLY AND COMPANY (US) | 1998-11-19 | — | — | WO | disclosed |
| EP-0670310-B1 | Bisulfite adducts of arginine aldehydes useful as thrombin inhibitors and as anticoagulants | LILLY CO ELI (US) | 1998-09-02 | — | — | EP | disclosed |
| US-5726159-A | PEPTIDE THROMBIN INHIBITORS | ELI LILLY AND COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5710130-A | HETEROCYCLIC SYNTHETIC PEPTIDES | ELI LILLY AND COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| US-5707966-A | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| US-5705487-A | PEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| CN-1147205-A | antithrombotic agent | LILLY CO ELI (US) | 1997-04-09 | — | — | CN | disclosed |
| EP-0672658-A1 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1995023609-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |
| EP-0670310-A1 | Bisulfite adducts of arginine aldehydes useful as thrombin inhibitors and as anticoagulants | ELI LILLY AND COMPANY (US) | 1995-09-06 | — | — | EP | disclosed |