Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7513716 | 0.99 | PAX8 (0.30) | PAX8 | |
| Hydrochloric Acid SCHEMBL7517092 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL7513738 | 0.72 | SCN9A (0.33) | — | |
| Hydrochloric Acid SCHEMBL7514186 | 0.72 | SLC6A2 (0.30) | — | |
| SCHEMBL7144487 | 0.69 | SLC6A4 (0.36) | — | |
| SCHEMBL7146409 | 0.68 | PAX8 (0.35) | PAX8 | |
| SCHEMBL7139136 | 0.67 | POLB (0.30) | — | |
| Hydrochloric Acid SCHEMBL7513708 | 0.67 | PAX8 (0.35) | PAX8 | |
| Hydrochloric Acid SCHEMBL7510456 | 0.67 | — | — | |
| SCHEMBL7140351 | 0.66 | SLC6A4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192122-B1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| EP-1192122-A1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076953-A1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2000-12-21 | — | — | WO | disclosed |