Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140351 | 0.80 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL7508322 | 0.79 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7146417 | 0.69 | PAX8 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7513716 | 0.68 | PAX8 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7517092 | 0.68 | — | — | |
| SCHEMBL27510859 | 0.68 | HRH3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7513738 | 0.67 | SCN9A (0.33) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6139799 | 0.67 | LMNA (0.60) | — | |
| SCHEMBL7144485 | 0.66 | ALDH1A1 (0.32) | SLC6A3 | |
| SCHEMBL7144483 | 0.66 | CHRM2 (0.33) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192122-B1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| US-6482986-B1 | Benzene derivatives, preparation method and pharmaceutical compositions containing same | SANOFI-SYNTHELABO (FR) | 2002-11-19 | — | — | US | disclosed |
| EP-1192122-A1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076953-A1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2000-12-21 | — | — | WO | disclosed |