SCHEMBL7146633

SCHEMBL7146633

C[C@H](N)C(=O)NC(=O)[C@@H]1CC(C2CCCCC2)CN1CC1CCC(C(=N)N)=CN1CC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7147702 0.99
SCHEMBL7144656 0.73 F2 (0.45)
Hydrochloric Acid SCHEMBL7148146 0.73 F2 (0.46)
SCHEMBL7247787 0.70 F2 (0.35)
SCHEMBL7253220 0.70
Hydrochloric Acid SCHEMBL7158175 0.69 F2 (0.36)
Hydrochloric Acid SCHEMBL7159952 0.69
SCHEMBL7359335 0.69
Hydrochloric Acid SCHEMBL8694344 0.69 CPB1 (0.32)
SCHEMBL7101675 0.69 PTGER4 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1515550-A Thrombosis resisting preparation 2004-07-28 CN claimed
EP-1361212-A1 Peptide derivatives as antithrombotic agents AstraZeneca AB (SE) 2003-11-12 EP claimed
CN-1147205-A antithrombotic agent LILLY CO ELI (US) 1997-04-09 CN claimed
EP-0672658-A1 Antithrombotic agents ELI LILLY AND COMPANY (US) 1995-09-20 EP claimed
WO-1995023609-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1995-09-08 WO claimed