Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506277 | 0.92 | TSHR (0.56) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28123718 | 0.92 | TSHR (0.56) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylonitrile SCHEMBL27674353 | 0.88 | THRB (0.42) | TSHRALDH1A1CYP3A4THRBCHRM2 | |
| SCHEMBL1538397 | 0.87 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylonitrile SCHEMBL7151502 | 0.85 | TSHR (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9770098 | 0.85 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL16053387 | 0.85 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28514930 | 0.84 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylonitrile SCHEMBL9562747 | 0.84 | THRB (0.46) | TSHRALDH1A1THRB | |
| Acrylonitrile SCHEMBL8964274 | 0.84 | TSHR (0.56) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054465-B1 | Polyelectrolytic gel | TOYO BOSEKI (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1054465-A1 | Polyelectrolytic gel | Toyo Boseki Kabushiki Kaisha (JP) | 2000-11-22 | — | — | EP | disclosed |