Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 12/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140923 | 0.83 | NCF1 (0.46) | MEN1KMT2ANPY5RMAPK1HSD17B10 | |
| SCHEMBL5408413 | 0.82 | MEN1 (0.46) | MEN1KMT2ANPY5RMAPK1HSD17B10 | |
| SCHEMBL7147827 | 0.80 | MEN1 (0.49) | MEN1KMT2ANPY5REGLN1 | |
| SCHEMBL5397682 | 0.74 | NPY5R (0.58) | MEN1KMT2ANPY5RMAPK1HSD17B10 | |
| SCHEMBL5419215 | 0.71 | NPY5R (0.61) | MEN1KMT2ANPY5RMAPK1HSD17B10 | |
| SCHEMBL5405088 | 0.71 | HRH4 (0.64) | MEN1KMT2ANPY5RMAPK1HSD17B10 | |
| SCHEMBL5406183 | 0.70 | MEN1 (0.53) | MEN1KMT2ANPY5RMAPK1HSD17B10 | |
| SCHEMBL5404393 | 0.70 | MEN1 (0.53) | MEN1KMT2ANPY5RMAPK1HSD17B10 | |
| SCHEMBL5402310 | 0.69 | HRH4 (0.62) | MEN1KMT2ANPY5RENPP1KDM4E | |
| SCHEMBL22911968 | 0.69 | MEN1 (0.51) | MEN1KMT2ANPY5RMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318981-A2 | QUINOLINE AND QUINAZOLINE DERIVATIVES AS LIGANDS FOR THE NEUROPEPTIDE Y RECEPTOR | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002020488-A2 | QUINOLINE AND QUINAZOLINE DERIVATIVES AS LIGANDS FOR THE NEUROPEPTIDE Y RECEPTOR | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-14 | — | — | WO | disclosed |