SCHEMBL7146879

SCHEMBL7146879

C=CC(=O)OCC(O)C(CCC)Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 5/20 0.46
TSHR P16473 3/20 0.42
THRA P10827 1/20 0.37
ALDH1A1 P00352 1/20 0.37
PPARG P37231 2/20 0.36
PPARA Q07869 2/20 0.36
HPGD P15428 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
POLB P06746 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
KDM4C Q9H3R0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28859172 0.83 THRB (0.49) THRBTSHRTHRAALDH1A1PPARG
SCHEMBL11027850 0.82 THRB (0.54) THRBTSHRALDH1A1PPARGPPARA
SCHEMBL28980937 0.81 THRB (0.50) THRBTSHRALDH1A1LMNAL3MBTL1
SCHEMBL19583227 0.79 THRB (0.50) THRBTSHRALDH1A1PPARGPPARA
SCHEMBL232073 0.79 TSHR (0.47) THRBTSHRTHRAALDH1A1HPGD
SCHEMBL28531263 0.78 TSHR (0.52) THRBTSHRTHRAALDH1A1PPARG
SCHEMBL181503 0.78 THRB (0.55) THRBTSHRALDH1A1PPARGPPARA
SCHEMBL28816832 0.78 THRB (0.44) THRBTSHRALDH1A1HPGDTDP1
SCHEMBL28859164 0.77 THRB (0.51) THRBTSHRALDH1A1PPARGPPARA
SCHEMBL181493 0.76 TSHR (0.56) THRBTSHRALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6524771-B2 Photopolymerizable gel NIPPON SHEET GLASS CO., LTD. (JP) 2003-02-25 US disclosed
US-6479193-B1 COMPRISING A GEL HAVING A NETWORK STRUCTURE OF AN INORGANIC SUBSTANCE AND A POLYMER WHICH IS FROM A PHOTOPOLYMERIZABLE COMPOUND NIPPON SHEET GLASS CO., LTD. (JP) 2002-11-12 US disclosed
US-20020004172-A1 Optical recording film and process for production thereof MAEDA KOICHI (JP) 2002-01-10 US disclosed