Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11027850 | 0.87 | THRB (0.54) | THRBTSHRALDH1A1MTNR1AMTNR1B | |
| SCHEMBL181493 | 0.84 | TSHR (0.56) | THRBTSHRALDH1A1MTNR1AMTNR1B | |
| SCHEMBL19583227 | 0.83 | THRB (0.50) | THRBTSHRALDH1A1MTNR1AMTNR1B | |
| SCHEMBL181503 | 0.82 | THRB (0.55) | THRBTSHRALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7146879 | 0.81 | THRB (0.46) | THRBTSHRALDH1A1MTNR1AMTNR1B | |
| Diphenylether SCHEMBL6002228 | 0.81 | THRB (0.54) | THRBTSHRALDH1A1LMNAGAA | |
| SCHEMBL28450602 | 0.80 | THRB (0.57) | THRBTSHRALDH1A1MTNR1AMTNR1B | |
| SCHEMBL28816832 | 0.79 | THRB (0.44) | THRBTSHRALDH1A1LMNACYP1A2 | |
| SCHEMBL28880043 | 0.79 | TSHR (0.46) | THRBTSHRALDH1A1L3MBTL1 | |
| SCHEMBL28859164 | 0.78 | THRB (0.51) | THRBTSHRALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114767549-A | Photochromic dental composite material and preparation method thereof | 日照沪鸽生物材料有限公司 | 2022-07-22 | — | — | CN | disclosed |