Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3890180 | 0.87 | MAPT (0.48) | MEN1KMT2AMAPTL3MBTL1NPC1 | |
| SCHEMBL8391027 | 0.85 | CYP2C9 (0.47) | MEN1KMT2AMAPTL3MBTL1NPC1 | |
| SCHEMBL12923595 | 0.82 | MAPT (0.45) | MEN1KMT2AMAPTL3MBTL1NPC1 | |
| SCHEMBL9176269 | 0.82 | MAPT (0.47) | MEN1KMT2AMAPTL3MBTL1NPC1 | |
| SCHEMBL7194575 | 0.82 | MAPT (0.44) | MEN1KMT2AMAPTL3MBTL1NPC1 | |
| SCHEMBL9115816 | 0.81 | MAPT (0.42) | MEN1KMT2AMAPTL3MBTL1NPC1 | |
| SCHEMBL7186463 | 0.81 | MAPT (0.42) | MEN1KMT2AMAPTL3MBTL1NPC1 | |
| SCHEMBL1986614 | 0.81 | LMNA (0.39) | MEN1KMT2AMAPTL3MBTL1NPC1 | |
| SCHEMBL9114656 | 0.80 | MAPT (0.43) | MEN1KMT2AMAPTL3MBTL1NPC1 | |
| SCHEMBL29860188 | 0.80 | LMNA (0.41) | MEN1KMT2AMAPTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145760-A | POSITIVE-WORKING PHOTOSENSITIVE ELECTROSTATIC MASTER WITH IMPROVED INVIRONMENTAL LATITUDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-08 | — | — | US | claimed |
| US-4945020-A | MIXTURE OF POLYMIERC BINDER, PHOTOOXIDANT, LEUCO DYE, HALOGENATED HYDROCARBON AND PLASTICIZER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-07-31 | — | — | US | claimed |
| US-6524763-B1 | Leuco compounds and organic halogen compounds; color when selectively sensitized by ionizing radiation (especially by low doses); detection of ionizing radiation | THE JAPAN ATOMIC POWER COMPANY (JP) | 2003-02-25 | — | — | US | disclosed |
| US-5145760-A | POSITIVE-WORKING PHOTOSENSITIVE ELECTROSTATIC MASTER WITH IMPROVED INVIRONMENTAL LATITUDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-08 | — | — | US | disclosed |
| US-4945020-A | MIXTURE OF POLYMIERC BINDER, PHOTOOXIDANT, LEUCO DYE, HALOGENATED HYDROCARBON AND PLASTICIZER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-07-31 | — | — | US | disclosed |