Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14875145 | 0.83 | PLCG1 (0.42) | PLCG1HTTPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL14875202 | 0.79 | MAOB (0.43) | PLCG1HTTPOLBSMN1; SMN2RAB9A | |
| SCHEMBL14875135 | 0.78 | MAOB (0.42) | PLCG1HTTPOLBSMN1; SMN2RAB9A | |
| SCHEMBL10757697 | 0.78 | ELANE (0.42) | PLCG1HTTPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL10757693 | 0.78 | ELANE (0.42) | PLCG1HTTPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL10757699 | 0.78 | ELANE (0.42) | PLCG1HTTPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL884743 | 0.77 | ALDH1A1 (0.38) | PLCG1HTTPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL4879120 | 0.77 | ALDH1A1 (0.38) | PLCG1HTTPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL9198910 | 0.77 | PLCG1 (0.42) | PLCG1HTTPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL8817335 | 0.76 | PLCG1 (0.37) | PLCG1POLBSMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100800-B1 | NOVEL C-2 S/O- AND S/N FORMALDEHYDE ACETAL DERIVATIVES OF CARBAPENEM-3-CARBOXYLIC ACIDS AND THEIR USE AS ANTIBIOTICS AND BETA-LACTAMASE INHIBITORS | PFAENDLER HANS RUDOLF PROF (DE) | 2003-06-25 | — | — | EP | disclosed |