Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL884743 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL4779818 | 0.90 | TDP1 (0.36) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL11132625 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL11131913 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL7146947 | 0.77 | PLCG1 (0.39) | ALDH1A1MAPTHPGDPLCG1HTT | |
| SCHEMBL14875145 | 0.76 | PLCG1 (0.42) | ALDH1A1MAPTHPGDPLCG1HTT | |
| SCHEMBL11130637 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL14875202 | 0.72 | MAOB (0.43) | ALDH1A1MAPTPLCG1HTTRAB9A | |
| SCHEMBL14875135 | 0.71 | MAOB (0.42) | ALDH1A1MAPTPLCG1HTTRAB9A | |
| SCHEMBL9640936 | 0.71 | FAP (0.43) | ALDH1A1MAPTHPGDATMPLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934221-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF BETA-LACTAM ANTIBIOTIC | Orchid Chemicals and Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007031858-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF BETA-LACTAM ANTIBIOTIC | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2007-03-22 | — | — | WO | disclosed |