Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141011 | 0.90 | CYP2C9 (0.47) | ALDH1A1TSHRCHRM1CYP2C9CYP2C19 | |
| SCHEMBL7145029 | 0.87 | HPGD (0.42) | ALDH1A1TSHRCHRM1EPHX2PREP | |
| SCHEMBL7148150 | 0.86 | CHRM1 (0.46) | ALDH1A1TSHRCHRM1PREPCYP2C9 | |
| SCHEMBL7139804 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TSHRCHRM1EPHX2PREP | |
| SCHEMBL7143115 | 0.84 | MEN1 (0.43) | CHRM1MEN1KMT2AUSP2POLB | |
| SCHEMBL7146507 | 0.84 | CYP2C9 (0.47) | ALDH1A1TSHRCHRM1PREPCYP2C9 | |
| SCHEMBL7145105 | 0.83 | CHRM1 (0.44) | ALDH1A1TSHRCHRM1EPHX2PREP | |
| SCHEMBL7148318 | 0.82 | CHRM1 (0.43) | ALDH1A1TSHRCHRM1EPHX2PREP | |
| SCHEMBL7146457 | 0.82 | CHRM1 (0.43) | ALDH1A1TSHRCHRM1PREPCYP2C9 | |
| SCHEMBL3479834 | 0.81 | KMT2A (0.48) | ALDH1A1TSHRCHRM1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322642-A2 | sHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES BEARING BOTH LIPOPHILIC AND IONISABLE MOIETIES AS INHIBITORS OF PROTEIN JUNKINASES | Applied Research Systems ARS Holding N.V. (AN) | 2003-07-02 | — | — | EP | claimed |
| WO-2002026733-A2 | sHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES BEARING BOTH LIPOPHILIC AND IONISABLE MOIETIES AS INHIBITORS OF PROTEIN JUNKINASES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-04-04 | — | — | WO | claimed |