Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20528165 | 0.81 | TSHR (0.43) | ZDHHC7MAPTTDP1MEN1KMT2A | |
| SCHEMBL20528140 | 0.80 | TSHR (0.42) | ZDHHC7MAPTGPR84NAAADGKA | |
| SCHEMBL9010353 | 0.80 | ZDHHC7 (0.46) | ZDHHC7MAPTTDP1MEN1KMT2A | |
| SCHEMBL28123196 | 0.80 | ALDH1A1 (0.52) | ZDHHC7MAPTTDP1MEN1KMT2A | |
| SCHEMBL7998406 | 0.78 | ALDH1A1 (0.50) | ZDHHC7MAPTMEN1KMT2AGPR84 | |
| SCHEMBL7775835 | 0.78 | NAAA (0.55) | ZDHHC7MAPTNAAAALDH1A1 | |
| SCHEMBL7781071 | 0.78 | NAAA (0.55) | ZDHHC7MAPTNAAAALDH1A1 | |
| SCHEMBL22026509 | 0.78 | NAAA (0.55) | ZDHHC7MAPTNAAAALDH1A1 | |
| SCHEMBL7768452 | 0.78 | NAAA (0.55) | ZDHHC7MAPTNAAAALDH1A1 | |
| SCHEMBL22026511 | 0.78 | NAAA (0.55) | ZDHHC7MAPTNAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6525197-B1 | Producing chemical intermediates for such as epothilone or epothilone analogues synthesis | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2003-02-25 | — | — | US | disclosed |