SCHEMBL936368

SCHEMBL936368

N[C@H](CCS)C(=O)OC(=O)[C@H](N)CCS

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 8/20 0.41
ANPEP P15144 3/20 0.41
PTGS1 P23219 1/20 0.39
SLC7A11 Q9UPY5 1/20 0.39
FOLH1 Q04609 1/20 0.32
GRM8 O00222 1/20 0.31
GRM6 O15303 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GSR P00390 1/20 0.31
CYP1A2 P05177 1/20 0.31
GRIK1 P39086 1/20 0.31
GRM5 P41594 1/20 0.31
GRIA1 P42261 1/20 0.31
GRIA2 P42262 1/20 0.31
GRIA3 P42263 1/20 0.31
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
GRIA4 P48058 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5988945 0.93 PTGS1 (0.44) ENPEPANPEPPTGS1SLC7A11
SCHEMBL380191 0.89 ENPEP (0.35) ENPEPANPEPPTGS1SLC7A11GRIN2D
SCHEMBL7147125 0.88
SCHEMBL7147126 0.88
SCHEMBL4439365 0.87 ANPEP (0.36) ENPEPANPEPPTGS1SLC7A11
SCHEMBL9052422 0.86 GSR (0.52) GSR
SCHEMBL1486704 0.85 ENPEP (0.41) ENPEPANPEPPTGS1SLC7A11FOLH1
SCHEMBL7692152 0.85 ENPEP (0.39) ENPEPANPEPPTGS1SLC7A11FOLH1
SCHEMBL2418306 0.84 ANPEP (0.42) ENPEPANPEP
SCHEMBL16694055 0.83 HSD17B10 (0.38) ENPEPANPEPPTGS1SLC7A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2456852-A1 CELL-BASED SYSTEMS FOR PRODUCTION OF METHYL FORMATE The Regents of the University of California (US) 2012-05-30 EP disclosed
WO-2011011627-A1 CELL-BASED SYSTEMS FOR PRODUCTION OF METHYL FORMATE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-27 WO disclosed
EP-2222833-A1 INDUSTRIAL PRODUCTION OF ORGANIC COMPOUNDS USING RECOMBINANT ORGANISMS EXPRESSING METHYL HALIDE TRANSFERASE The Regents of the University of California (US) 2010-09-01 EP disclosed
WO-2009073560-A1 INDUSTRIAL PRODUCTION OF ORGANIC COMPOUNDS USING RECOMBINANT ORGANISMS EXPRESSING METHYL HALIDE TRANSFERASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-06-11 WO disclosed
CN-100404688-C High specificity homocysteine assays for biological samples ANTICANCER INC (US) 2008-07-23 CN disclosed
CN-1305844-C Dialkyl-beta-propiothetin haloid acid salt and carboxylate preparation method BEIJING GELIN FUCHENG TECHNOLO (CN) 2007-03-21 CN disclosed
CN-1762997-A Dialkyl-beta-propiothetin haloid acid salt and carboxylate preparation method BEIJING GELIN FUCHENG TECHNOLO (CN) 2006-04-26 CN disclosed
CN-1268978-A High specificity homocysteine assays for biological samples ANTICANCER INC (US) 2000-10-04 CN disclosed