SCHEMBL7147228

SCHEMBL7147228

CCN(c1ccccc1)c1ccc(C=O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
ALDH1A3 P47895 2/20 0.59
ALDH3A1 P30838 1/20 0.59
NR3C2 P08235 1/20 0.53
CYP2A6 P11509 4/20 0.52
CYP2A13 Q16696 1/20 0.52
TSHR P16473 2/20 0.42
GLA P06280 1/20 0.42
NPSR1 Q6W5P4 2/20 0.41
MAPT P10636 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
APAF1 O14727 1/20 0.41
CASP3 P42574 1/20 0.41
CASP6 P55212 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
RELA Q04206 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17508303 0.87 ALDH1A1 (0.53) ALDH1A1ALDH1A3ALDH3A1NR3C2CYP2A6
SCHEMBL7149333 0.85 NR3C2 (0.60) ALDH1A1NR3C2TSHRGLANPSR1
SCHEMBL7150218 0.84 ALDH1A1 (0.50) ALDH1A1ALDH1A3ALDH3A1NR3C2TSHR
SCHEMBL11859243 0.84 CYP2A6 (0.64) ALDH1A1ALDH1A3ALDH3A1NR3C2CYP2A6
SCHEMBL17508208 0.84 ALDH1A1 (0.50) ALDH1A1ALDH1A3ALDH3A1NR3C2CYP2A6
SCHEMBL181026 0.83 ALDH1A1 (0.59) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL851178 0.83 ALDH1A1 (0.59) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL2199745 0.83 ALDH1A1 (0.59) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL28032989 0.83 ALDH1A1 (0.59) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13
SCHEMBL13649928 0.83 ALDH1A1 (0.59) ALDH1A1ALDH1A3ALDH3A1CYP2A6CYP2A13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107056636-B Oseltamivir derivative and preparation method and application thereof 山东大学 2021-05-11 CN disclosed
WO-2016019588-A1 OXACAZONE COMPOUNDS TO TREAT CLOSTRIDIUM DIFFICILE THE BROAD INSTITUTE, INC. (US) 2016-02-11 WO disclosed
WO-2016019588-A1 OXACAZONE COMPOUNDS TO TREAT CLOSTRIDIUM DIFFICILE THE BROAD INSTITUTE, INC. (US) 2016-02-11 WO disclosed
CN-1119371-C Organosilicon-modified charge transporting compound and curable composition containing compound and having charge transporting ability DOW CORNING ASIA LTD (JP) 2003-08-27 CN disclosed
EP-0771805-B1 Silicon containing charge transport compounds and curable compositions thereof DOW CORNING ASIA LTD (JP) 2003-05-02 EP disclosed
EP-0875791-B1 An electrophotographic photosensitive member, a process-cartridge inclusive thereof, and an image forming apparatus CANON KK (JP) 2002-07-24 EP disclosed
US-6376695-B1 ORGANOSILICON COMPOUND CONTAINING AMINE GROUP DOW CORNING ASIA LTD. (JP) 2002-04-23 US disclosed
US-6296978-B1 LIGHT SENSITIVE ELEMENTS FOR IMAGES CANON KABUSHIKI KAISHA (JP) 2001-10-02 US disclosed
EP-0772091-B1 An electrophotographic photosensitive member, a process-cartridge inclusive thereof, and an image forming apparatus CANON KK (JP) 2001-02-28 EP disclosed
US-5888690-A Electrophotographic photosensitive member, a process-cartridge inclusive thereof, and an image forming apparatus CANON KABUSHIKI KAISHA (JP) 1999-03-30 US disclosed
US-5879847-A Electrophotographic photosensitive member, a process-cartridge inclusive thereof and an image forming apparatus CANON KABUSHIKI KAISHA (JP) 1999-03-09 US disclosed
EP-0875791-A2 An electrophotographic photosensitive member, a process-cartridge inclusive thereof, and an image forming apparatus CANON KABUSHIKI KAISHA (JP) 1998-11-04 EP disclosed
CN-1156849-A Organosilicon-modified charge transporting compound and curable composition containing compound and having charge transporting ability DOW CORNING ASIA LTD (JP) 1997-08-13 CN disclosed
EP-0772091-A1 An electrophotographic photosensitive member, a process-cartridge inclusive thereof, and an image forming apparatus CANON KABUSHIKI KAISHA (JP) 1997-05-07 EP disclosed
EP-0771805-A1 Silicon containing charge transport compounds and curable compositions thereof Dow Corning Asia, Ltd. (JP) 1997-05-07 EP disclosed
US-4513142-A Preparation of cationic methine dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1985-04-23 US disclosed
US-4110070-A QUATERNIZING INDOLENINE METHINE COMPOUND ON FIBERS TO FORM CATIONIC DYE HODOGAYA CHEMICAL CO., LTD. (JP) 1978-08-29 US disclosed
US-3975379-A METHINE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 US disclosed