SCHEMBL7150218

SCHEMBL7150218

C=Cc1ccc(N(CC)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
TSHR P16473 4/20 0.50
NR3C2 P08235 1/20 0.49
MAPT P10636 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RELA Q04206 1/20 0.39
ALDH3A1 P30838 1/20 0.39
ALDH1A3 P47895 1/20 0.39
GLA P06280 1/20 0.38
HCN1 O60741 2/20 0.38
HCN4 Q9Y3Q4 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
KDM4C Q9H3R0 1/20 0.37
APAF1 O14727 1/20 0.37
CASP3 P42574 1/20 0.37
CASP6 P55212 1/20 0.37
SENP8 Q96LD8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23933935 0.92 ALDH1A1 (0.52) ALDH1A1TSHRNR3C2MAPTNPSR1
SCHEMBL13777492 0.86 ALDH1A1 (0.46) ALDH1A1TSHRNR3C2MAPTNPSR1
SCHEMBL7149333 0.85 NR3C2 (0.60) ALDH1A1TSHRNR3C2MAPTCRHBP
SCHEMBL7147228 0.84 ALDH1A1 (0.59) ALDH1A1TSHRNR3C2MAPTCRHBP
SCHEMBL172194 0.83 ALDH1A1 (0.59) ALDH1A1TSHRMAPTCRHBPCRHR2
SCHEMBL1177035 0.83 ALDH1A1 (0.59) ALDH1A1TSHRMAPTCRHBPCRHR2
SCHEMBL12114947 0.83 ALDH1A1 (0.59) ALDH1A1TSHRMAPTCRHBPCRHR2
SCHEMBL99027 0.83 ALDH1A1 (0.59) ALDH1A1TSHRMAPTCRHBPCRHR2
SCHEMBL6567347 0.82 NR3C2 (0.57) ALDH1A1TSHRNR3C2MAPTCRHBP
SCHEMBL409370 0.82 NR3C2 (0.57) ALDH1A1TSHRNR3C2MAPTCRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1119371-C Organosilicon-modified charge transporting compound and curable composition containing compound and having charge transporting ability DOW CORNING ASIA LTD (JP) 2003-08-27 CN disclosed
EP-0771805-B1 Silicon containing charge transport compounds and curable compositions thereof DOW CORNING ASIA LTD (JP) 2003-05-02 EP disclosed
EP-0875791-B1 An electrophotographic photosensitive member, a process-cartridge inclusive thereof, and an image forming apparatus CANON KK (JP) 2002-07-24 EP disclosed
US-6376695-B1 ORGANOSILICON COMPOUND CONTAINING AMINE GROUP DOW CORNING ASIA LTD. (JP) 2002-04-23 US disclosed
US-6296978-B1 LIGHT SENSITIVE ELEMENTS FOR IMAGES CANON KABUSHIKI KAISHA (JP) 2001-10-02 US disclosed
EP-0772091-B1 An electrophotographic photosensitive member, a process-cartridge inclusive thereof, and an image forming apparatus CANON KK (JP) 2001-02-28 EP disclosed
US-5888690-A Electrophotographic photosensitive member, a process-cartridge inclusive thereof, and an image forming apparatus CANON KABUSHIKI KAISHA (JP) 1999-03-30 US disclosed
US-5879847-A Electrophotographic photosensitive member, a process-cartridge inclusive thereof and an image forming apparatus CANON KABUSHIKI KAISHA (JP) 1999-03-09 US disclosed
EP-0875791-A2 An electrophotographic photosensitive member, a process-cartridge inclusive thereof, and an image forming apparatus CANON KABUSHIKI KAISHA (JP) 1998-11-04 EP disclosed
CN-1156849-A Organosilicon-modified charge transporting compound and curable composition containing compound and having charge transporting ability DOW CORNING ASIA LTD (JP) 1997-08-13 CN disclosed
EP-0772091-A1 An electrophotographic photosensitive member, a process-cartridge inclusive thereof, and an image forming apparatus CANON KABUSHIKI KAISHA (JP) 1997-05-07 EP disclosed
EP-0771805-A1 Silicon containing charge transport compounds and curable compositions thereof Dow Corning Asia, Ltd. (JP) 1997-05-07 EP disclosed
EP-0304613-B1 BENZOPYRAN DERIVATIVES BASF Aktiengesellschaft (DE) 1991-06-26 EP disclosed
US-4958021-A PRESSURE AND HEAT SENSITIVE RECORDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 1990-09-18 US disclosed
EP-0304613-A1 Benzopyran derivatives BASF Aktiengesellschaft (DE) 1989-03-01 EP disclosed