Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008386 | 0.91 | OPRM1 (0.38) | HTR2ASLC6A2SLC6A4SLC6A3MMP2 | |
| SCHEMBL11715846 | 0.87 | HTR2A (0.41) | HTR2ASLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL9289176 | 0.80 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9523728 | 0.79 | SLC6A2 (0.40) | HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27825135 | 0.79 | TSHR (0.39) | HTR2ASLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL14028104 | 0.79 | SLC6A4 (0.60) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1036893 | 0.77 | HTR2A (0.38) | HTR2ASLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL10812665 | 0.76 | KDM1A (0.38) | SLC6A2SLC6A3HTR1A | |
| SCHEMBL27885042 | 0.76 | KDM1A (0.38) | SLC6A2SLC6A3HTR1A | |
| SCHEMBL891327 | 0.76 | OPRM1 (0.36) | SLC6A2SLC6A4SLC6A3MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102344135-A | Surface modified nanodiamond and method of forming the same | IND TECH RES INST | 2012-02-08 | — | — | CN | disclosed |
| CN-1419545-A | 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors | WYETH CORP (US) | 2003-05-21 | — | — | CN | disclosed |
| EP-1268431-A1 | 3-CYANOQUINOLINES,3-CYANO-1,6-NAPHTHYRIDINES, AND 3-CYANO-1,7-NAPHTHYRIDINES AS PROTEIN KINASE INHIBITORS | Wyeth (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001072711-A1 | 3-CYANOQUINOLINES,3-CYANO-1,6-NAPHTHYRIDINES, AND 3-CYANO-1,7-NAPHTHYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH (US) | 2001-10-04 | — | — | WO | disclosed |
| EP-0008686-B1 | SYNTHESIS OF PHENYL-PROPYL MORPHOLINE AND PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-04-20 | — | — | EP | disclosed |
| EP-0008686-A2 | Synthesis of phenyl-propyl morpholine and piperidine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-03-19 | — | — | EP | disclosed |