Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150453 | 0.90 | PTGS2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL7147957 | 0.83 | PTGS2 (0.53) | PTGS2PTGS1CA12CA2CA9 | |
| SCHEMBL6095624 | 0.81 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL215654 | 0.81 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL7140520 | 0.80 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL6094518 | 0.76 | NFKB1 (0.43) | PTGS2PTGS1PDK1PDK2PDK3 | |
| SCHEMBL7150416 | 0.75 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL214145 | 0.74 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL6093423 | 0.74 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7149758 | 0.73 | PTGS2 (0.53) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |