Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 8/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091621 | 0.90 | VDR (0.54) | VDRHDAC3HDAC6 | |
| SCHEMBL25410122 | 0.89 | VDR (0.53) | VDRHDAC3HDAC6 | |
| SCHEMBL25894696 | 0.89 | VDR (0.53) | VDRHDAC3HDAC6 | |
| SCHEMBL25410119 | 0.89 | VDR (0.53) | VDRHDAC3HDAC6 | |
| SCHEMBL25894630 | 0.89 | VDR (0.53) | VDRHDAC3HDAC6 | |
| SCHEMBL25314638 | 0.88 | VDR (0.56) | VDR | |
| SCHEMBL25314634 | 0.88 | VDR (0.56) | VDR | |
| SCHEMBL8090252 | 0.88 | VDR (0.56) | VDR | |
| SCHEMBL25895008 | 0.88 | VDR (0.56) | VDR | |
| SCHEMBL25438435 | 0.87 | VDR (0.51) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998455-B1 | DIHOMO-SECO-CHOLESTANES WITH TWO UNSATURATED BONDS IN THE SIDE CHAIN | HOFFMANN LA ROCHE (CH) | 2003-10-01 | — | — | EP | disclosed |
| US-5994569-A | USEFUL IN THE TREATMENT OR PREVENTION OF VITAMIN D DEPENDENT DISORDERS AND OF IL-12-DEPENDENT AUTOIMMUNE DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1999-11-30 | — | — | US | disclosed |