SCHEMBL7147410

SCHEMBL7147410

C[AsH]c1c(N)nn(C)c1N

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 1/20 0.34
CDK1 P06493 1/20 0.34
CDK4 P11802 1/20 0.34
CCNB1 P14635 1/20 0.34
CCND1 P24385 1/20 0.34
CCNE1 P24864 1/20 0.34
CDK2 P24941 1/20 0.34
CDK9 P50750 1/20 0.34
GAA P10253 1/20 0.33
PKM P14618 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33726 0.69
SCHEMBL219198 0.67
Hydrochloric Acid SCHEMBL922698 0.65 GAA (0.56) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL11549305 0.64 PDPK1 (0.42) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL34103 0.62 CCNT1 (0.38) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL11543788 0.60 LMNA (0.41) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL10467153 0.59 PKM (0.33) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL14039865 0.59
SCHEMBL18197997 0.57
SCHEMBL2467004 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1341504-A2 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING AN ASSOCIATIVE POLYMER AND A PEARLING AGENT L'OREAL (FR) 2003-09-10 EP disclosed
WO-2002045651-A2 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING AN ASSOCIATIVE POLYMER AND A PEARLING AGENT L'OREAL (FR) 2002-06-13 WO disclosed