Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | FUBP1 | Q96AE4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3010846 | 0.85 | GAA (0.64) | L3MBTL1GAAPTGES2NPC1RAB9A | |
| SCHEMBL8648423 | 0.73 | TP53 (0.52) | L3MBTL1GAARAB9APOLBALDH1A1 | |
| SCHEMBL2633819 | 0.72 | GAA (0.67) | L3MBTL1GAAPTGES2NPC1RAB9A | |
| SCHEMBL1593778 | 0.72 | PTGES2 (0.67) | L3MBTL1GAAPTGES2NPC1RAB9A | |
| SCHEMBL3019078 | 0.71 | RAB9A (0.77) | L3MBTL1GAANPC1RAB9AALDH1A1 | |
| SCHEMBL1594800 | 0.70 | GAA (0.61) | L3MBTL1GAAPTGES2NPC1RAB9A | |
| SCHEMBL788538 | 0.69 | L3MBTL1 (0.65) | L3MBTL1NPC1RAB9APOLBCA1 | |
| SCHEMBL3687294 | 0.68 | NPC1 (0.41) | L3MBTL1GAAPTGES2NPC1RAB9A | |
| SCHEMBL7342487 | 0.67 | PFKFB3 (0.39) | L3MBTL1NPC1RAB9APOLBCA12 | |
| SCHEMBL6958046 | 0.67 | PFKFB3 (0.39) | L3MBTL1NPC1RAB9APOLBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283831-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2003-02-19 | — | — | EP | disclosed |
| WO-2001090090-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2001-11-29 | — | — | WO | disclosed |