Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723960 | 0.87 | CYP2A6 (0.44) | KDM4EMAPTGAAALDH1A1L3MBTL1 | |
| Benzene SCHEMBL28459864 | 0.85 | CYP2A6 (0.43) | KDM4EMAPTGAAALDH1A1L3MBTL1 | |
| SCHEMBL4586854 | 0.77 | CYP2A6 (0.40) | KDM4EMAPTGAAALDH1A1L3MBTL1 | |
| SCHEMBL9487879 | 0.76 | CYP2A6 (0.40) | KDM4EALDH1A1SMN1; SMN2NPC1 | |
| Fluorobenzene SCHEMBL28295266 | 0.76 | KDM4E (0.42) | KDM4EMAPTGAAALDH1A1LMNA | |
| SCHEMBL9380818 | 0.75 | ALDH1A1 (0.50) | KDM4EMAPTGAAALDH1A1LMNA | |
| SCHEMBL4585879 | 0.75 | PTPRC (0.40) | KDM4EMAPTGAAALDH1A1L3MBTL1 | |
| SCHEMBL498678 | 0.75 | DPP4 (0.51) | KDM4EMAPTGAAALDH1A1LMNA | |
| SCHEMBL698354 | 0.75 | DPP4 (0.51) | KDM4EMAPTGAAALDH1A1LMNA | |
| SCHEMBL28646041 | 0.75 | KDM4E (0.50) | KDM4EMAPTGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450796-A1 | BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003045385-A1 | BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-05 | — | — | WO | disclosed |