Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745486 | 0.83 | CHRM1 (0.35) | NR1H2 | |
| SCHEMBL6749623 | 0.81 | — | — | |
| SCHEMBL6749482 | 0.77 | HSD11B1 (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6749478 | 0.77 | HSD11B1 (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7143739 | 0.75 | NR1H2 (0.36) | NR1H2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6745589 | 0.74 | HSD11B1 (0.35) | — | |
| SCHEMBL6778656 | 0.74 | MEN1 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6778655 | 0.74 | MEN1 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6750578 | 0.72 | TPSAB1 (0.34) | — | |
| SCHEMBL6750582 | 0.72 | TPSAB1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |