Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | OGG1 | O15527 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5485349 | 0.85 | ESR1 (0.39) | ALDH1A1HPGDESR1HSD17B10MAPT | |
| SCHEMBL5471885 | 0.79 | ESR1 (0.49) | LMNATP53ALDH1A1POLBHPGD | |
| SCHEMBL6544700 | 0.73 | GAA (0.54) | LMNAALDH1A1HPGDESR1HSD17B10 | |
| SCHEMBL5471958 | 0.70 | ALDH1A1 (0.32) | ALDH1A1OPRD1ESR1HSD17B10TSHR | |
| SCHEMBL7534625 | 0.68 | LMNA (0.38) | LMNATP53POLB | |
| SCHEMBL27403915 | 0.68 | TSHR (0.49) | TP53ALDH1A1ESR1HSD17B10MAPT | |
| SCHEMBL7534627 | 0.67 | LMNA (0.40) | LMNATP53HPGDKDM4EMAOB | |
| SCHEMBL10717862 | 0.66 | GAA (0.43) | ALDH1A1HPGDKDM4EESR1HSD17B10 | |
| SCHEMBL4625144 | 0.66 | KMT2A (0.61) | LMNAALDH1A1HPGDESR1HSD17B10 | |
| SCHEMBL986872 | 0.65 | TSHR (0.41) | ALDH1A1ESR1HSD17B10TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512070-B2 | Comprise both a light emitting segment and a charge transport segment; may be A-B-A triblock copolymers, brush-type graft copolymers, or variations thereof. | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2003-01-28 | — | — | US | disclosed |
| US-20020045719-A1 | Dual purpose electroactive copolymers | HAWKER CRAIG JON (US) | 2002-04-18 | — | — | US | disclosed |
| US-6355756-B1 | GRAFT AND BLOCK POLYMERIZATION OF DIHALO-SUBSTITUTED POLYCYCLIC COMPOUNDS USING FREE RADICAL POLYMERIZATION CATALYST; SYNTHESIZING CHARGE TRANSPORT SEGMENTS; LIGHT EMITTING DIODES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2002-03-12 | — | — | US | disclosed |