Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1517769 | 0.86 | — | — | |
| SCHEMBL5327032 | 0.83 | CNR1 (0.53) | CASP2EPHX1MEN1KMT2ACNR1 | |
| SCHEMBL5327026 | 0.83 | CNR1 (0.53) | CASP2EPHX1MEN1KMT2ACNR1 | |
| SCHEMBL4649336 | 0.81 | ZDHHC20 (0.50) | CASP2EPHX1MEN1KMT2ACNR1 | |
| SCHEMBL10632393 | 0.81 | CASP2 (0.48) | CASP2EPHX1MEN1KMT2ACNR1 | |
| SCHEMBL5323738 | 0.79 | CNR1 (0.49) | CASP2EPHX1MEN1KMT2ACNR1 | |
| SCHEMBL5323744 | 0.79 | CNR1 (0.49) | CASP2EPHX1MEN1KMT2ACNR1 | |
| SCHEMBL10631439 | 0.79 | CASP2 (0.60) | CASP2EPHX1MEN1KMT2ACNR1 | |
| SCHEMBL22104112 | 0.77 | CASP2 (0.59) | CASP2EPHX1MEN1KMT2ANAAA | |
| SCHEMBL2318684 | 0.77 | CASP2 (0.71) | CASP2EPHX1MEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339669-A2 | N-ALKYLATED GABA COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB, S.A. (BE) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002042256-A2 | N-ALKYLATED GABA COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB, S.A. (BE) | 2002-05-30 | — | — | WO | disclosed |