Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749210 | 0.87 | HDAC6 (0.37) | HDAC6HDAC1 | |
| SCHEMBL6749494 | 0.81 | HDAC6 (0.35) | HDAC6HDAC1 | |
| SCHEMBL6751864 | 0.79 | HDAC6 (0.34) | HDAC6 | |
| SCHEMBL6749177 | 0.78 | RAB9A (0.43) | HDAC6HDAC1 | |
| SCHEMBL6745468 | 0.75 | HDAC6 (0.43) | HDAC6HDAC1 | |
| SCHEMBL6745730 | 0.74 | HDAC6 (0.43) | HDAC6 | |
| SCHEMBL6749176 | 0.73 | LMNA (0.47) | HDAC6 | |
| SCHEMBL6749091 | 0.73 | HDAC6 (0.43) | HDAC6HDAC1 | |
| SCHEMBL6747454 | 0.73 | HDAC6 (0.43) | HDAC6HDAC1 | |
| SCHEMBL6749341 | 0.72 | HDAC6 (0.39) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |