SCHEMBL7148200

SCHEMBL7148200

CNCS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.57
CYP2C9 P11712 3/20 0.57
CYP3A4 P08684 2/20 0.57
CYP2C19 P33261 2/20 0.57
MAPT P10636 4/20 0.56
ADAM17 P78536 1/20 0.56
GAA P10253 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TDP1 Q9NUW8 3/20 0.53
TP53 P04637 1/20 0.53
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
CYP1A2 P05177 2/20 0.47
CTSK P43235 1/20 0.47
HPGD P15428 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3975244 0.84 ALDH1A1 (0.59) ALDH1A1CYP2C9CYP3A4CYP2C19MAPT
SCHEMBL420473 0.81 ALDH1A1 (0.55) ALDH1A1CYP2C9CYP3A4CYP2C19MAPT
SCHEMBL20342110 0.81 CA1 (0.45) ALDH1A1CYP2C9CYP3A4CYP2C19MAPT
SCHEMBL13664878 0.79 ALDH1A1 (0.64) ALDH1A1CYP2C9CYP3A4CYP2C19MAPT
SCHEMBL13922066 0.79 ALDH1A1 (0.66) ALDH1A1CYP2C9CYP3A4CYP2C19MAPT
SCHEMBL3997583 0.78 ALDH1A1 (0.52) ALDH1A1CYP2C9CYP3A4CYP2C19MAPT
SCHEMBL6752911 0.78 ALDH1A1 (0.66) ALDH1A1CYP2C9CYP3A4CYP2C19MAPT
SCHEMBL3590596 0.78 ALDH1A1 (0.52) ALDH1A1CYP2C9CYP3A4CYP2C19MAPT
SCHEMBL21241027 0.78 ALDH1A1 (0.52) ALDH1A1CYP2C9CYP3A4CYP2C19MAPT
SCHEMBL11325997 0.78 ALDH1A1 (0.71) ALDH1A1CYP2C9CYP3A4CYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7479494-B2 3-monosubstituted tropane derivatives as nociceptin receptor ligands SCHERING CORPORATION (US) 2009-01-20 US disclosed
EP-0620929-B1 PHOTOGRAPHIC DISPERSION EASTMAN KODAK CO (US) 2003-10-01 EP disclosed
EP-0661588-B1 Color photographic element EASTMAN KODAK CO (US) 1999-10-20 EP disclosed
US-5468604-A Particle growth inhibition EASTMAN KODAK COMPANY (US) 1995-11-21 US disclosed
EP-0661588-A2 Color photographic element EASTMAN KODAK COMPANY (US) 1995-07-05 EP disclosed
US-4353979-A 5-PYRAZOLONE MAGENTA COUPLER AND HIGH BOILING PHOSPHONATE SOLVENT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1982-10-12 US disclosed
US-4326022-A FOR A HYDROPHOBIC COUPLER IN A SILVER HALIDE EMULSION KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1982-04-20 US disclosed
US-4127413-A PYRROLIDINONES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1978-11-28 US disclosed