Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752911 | 0.89 | ALDH1A1 (0.66) | ALDH1A1TDP1TP53MAPTADAM17 | |
| SCHEMBL15791835 | 0.84 | MAPT (0.70) | ALDH1A1TDP1TP53MAPTADAM17 | |
| SCHEMBL13686173 | 0.84 | ALDH1A1 (0.60) | ALDH1A1TDP1TP53MAPTADAM17 | |
| SCHEMBL11207452 | 0.83 | ALDH1A1 (1.00) | ALDH1A1TDP1TP53MAPTADAM17 | |
| SCHEMBL11268298 | 0.83 | NPC1 (0.58) | ALDH1A1TDP1TP53MAPTADAM17 | |
| SCHEMBL8799140 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TDP1TP53MAPTADAM17 | |
| SCHEMBL2344524 | 0.81 | KMT2A (0.61) | ALDH1A1TDP1TP53MAPTCYP3A4 | |
| SCHEMBL7743397 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TDP1TP53MAPTADAM17 | |
| SCHEMBL201255 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TDP1TP53MAPTADAM17 | |
| SCHEMBL28619945 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TDP1TP53MAPTADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307170-A | ACID CATALYST - AZO COUPLERS PROMOTE DISCOLORATION AND BLOOM RESISTANCE | JAMES RIVER GRAPHICS, INC. (US) | 1981-12-22 | — | — | US | claimed |
| US-10912755-B2 | Arginase inhibitors and their therapeutic applications | Oncoarendi Therapeutics S.A. (PL) | 2021-02-09 | — | — | US | disclosed |
| EP-3452485-B1 | ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | ONCOARENDI THERAPEUTICS SA (PL) | 2020-09-09 | — | — | EP | disclosed |
| US-10391077-B2 | Arginase inhibitors and their therapeutic applications | Oncoarendi Therapeutics S.A. (PL) | 2019-08-27 | — | — | US | disclosed |
| EP-3452485-A2 | ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | Oncoarendi Therapeutics SA (PL) | 2019-03-13 | — | — | EP | disclosed |
| US-20170319536-A1 | Arginase Inhibitors and Their Therapeutic Applications | Oncoarendi Therapeutics S.A. (PL) | 2017-11-09 | — | — | US | disclosed |
| WO-2017191130-A2 | ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | ONCOARENDI THERAPEUTICS SA (PL) | 2017-11-09 | — | — | WO | disclosed |
| US-4307170-A | ACID CATALYST - AZO COUPLERS PROMOTE DISCOLORATION AND BLOOM RESISTANCE | JAMES RIVER GRAPHICS, INC. (US) | 1981-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10391077-B2 | Arginase inhibitors and their therapeutic applications | ARG1, ARG2, ARGLU1 | ALDH1A1 675/4885TDP1 829/4885TP53 1854/4885 |
| US-20170319536-A1 | Arginase Inhibitors and Their Therapeutic Applications | ARG1, ARG2, ARGLU1 | ALDH1A1 675/4885TDP1 829/4885TP53 1854/4885 |
| US-10912755-B2 | Arginase inhibitors and their therapeutic applications | ARG1, ARG2, ARGLU1 | ALDH1A1 675/4885TDP1 829/4885TP53 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.